| 翻訳と辞書 |
| fibroblast growth factor 23 ： ウィキペディア英語版 |
fibroblast growth factor 23
Fibroblast growth factor 23 or FGF23 is a protein that in humans is encoded by the ''FGF23'' gene. FGF23 is a member of the fibroblast growth factor (FGF) family which is responsible for phosphate metabolism.
== Function ==
The main function of FGF23 seems to be regulation of phosphate concentration in plasma. FGF23 is secreted by Osteocytes in response to elevated Calcitriol. FGF23 acts on the kidneys, where it decreases the expression of NPT2, a sodium-phosphate cotransporter in the proximal tubule. Thus, FGF23 decreases the reabsorption and increases excretion of phosphate. FGF23 may also suppress 1-alpha-hydroxylase, reducing its ability to activate vitamin D and subsequently impairing calcium absorption.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「fibroblast growth factor 23」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|